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Tricia King

Professor    ,

Ph.D., University of Florida, 2000


Clinical Neuropsychology

Is Dr. King accepting a student for fall admission? 

My research program investigates the interacting biopsychosocial factors that contribute to optimal adaptive outcomes following neurodevelopmental disruption. My interest in brain-behavior relationships is broad, spanning a wide range of research methods, psychological domains, and populations. My research is focused on discovering what happens to the developing brain and to cognitive abilities across the lifespan many years after disorder onset (e.g., brain tumor, congenital heart disease). My team and I investigate white matter pathways using diffusion tensor imaging (DTI) and brain region activations using functional MRI (fMRI) to examine the neural mechanisms underlying both cognitive and social-emotional abilities of individuals. While I employ this comprehensive framework to examine the long-term outcomes of survivors of childhood brain tumors, I also have extended components of this work to other neurodevelopmental disorders by investigating predictors of adaptive outcomes and neuroimaging studies of cognition.

In 2013, my team and I successfully completed the 6-year Research Scholar Grant awarded by the American Cancer Society (ACS) for this program of research. One extension of this research is an ongoing collaboration with Dr. Tobey McDonald, funded by AFLAC Center and Children’s Health Care of Atlanta (CHOA)’s Pediatric Hematology/Oncology Center of Excellence, that examines single nucleotide polymorphisms relationship with cognitive and neuroimaging outcomes of survivors of cerebellar brain tumors. We also expanded this research to examine how these factors relate to sleep outcomes in survivors (funded by CHOA’s Center for Neurosciences Research). We have developed several multisite collaborations to validate our findings of host whole genome variations that are associated with cognitive outcomes of pediatric brain tumors survivors.

Most recently, I have assembled an exciting team of collaborators interested in optimizing brain health and cognitive outcomes of pediatric brain tumor survivors. We will examine host genomics of survivors with longitudinal neurocognitive performance and innovative structural and functional neuroimaging. In addition, we will identify the cognitive and brain health benefits of aerobic exercise in survivors. Integrating these unique and complementary data, our project will accelerate advancements in individualized precision medicine of the future resulting in prognostic and intervention clinical applications to mitigate neurotoxicities and to enable survivors to thrive.

Within this program of research, we are also interested in identifying efficient screening batteries that are sensitive to subtle cognitive changes to improve standard quality of care. Developing data driven algorithms for gold standard and computerized performance measures of cognitive skills will assist with early identification of individuals at risk for adverse long-term outcome. These data also will provide direction to the development of interventions to mitigate the severity of late effects and optimize adaptive outcomes across the lifespan.

Many of my students have developed clinical neuropsychological evaluation skills and research projects while contributing to these projects. See the video of our research team (at bottom of webpage); at the GSU/Ga Tech Center for Advanced Brain Imaging, where we conduct our research.

Developmental Neuropsychology Across the Lifespan (DNP-ATL)

DNP-ATL Research Team Website

All of these rewarding collaborations build upon my interests in optimizing outcomes of individuals with neurodevelopmental conditions across the lifespan.


For a complete list of publications see my bibliography

Recent Representative Peer Reviewed Publications
Student mentee co-authors’ names are italicized.

Siegel, B.I., King, T.Z., Rupji, M., Dwivedi, B., Carter, A.B., Kowalski, J., & MacDonald, T.J. (2019). Host whole genome variations are associated with neurocognitive outcome in survivors of pediatric medulloblastoma. Translational Oncology,12(7), 908-915. doi: 10.1016/j.tranon.2019.03.004

Panwala, T.F., Fox, M.E., Tucker, T.D., & King, T.Z. (in press, epub2019). The effects of radiation and sex differences on adaptive functioning in adult survivors of pediatric posterior fossa brain tumors. Journal of the International Neuropsychological Society. doi: 10.1017/S135561771900033X

Na, S., Li, L., Crosson, B., Dotson, V., MacDonald, T.J., Mao, H., & King, T.Z. (2018). White Matter Topology relates to cognitive flexibility and cumulative neurological risk in adult survivors of pediatric brain tumor. Neuroimage: Clinical, 20,485-497. DOI:10.1016/j.nicl.2018.08.015

King, T.Z., Ailion, AS., Fox, ME., & Hufstetler, S.M.  (2019). Neurodevelopmental model of long-term outcomes of adult survivors of childhood brain tumors. Child Neuropsychology, 25(1), 1-21.  DOI 10.1080/09297049.2017.1380178

Kautiainen, R.J., Na, S.D., & King, T.Z. (2019). Neurological Predictor Scale is associated with academic achievement in long-term survivors of childhood brain tumors. Journal of Neuro-Oncology, 142, 193-201. DOI: 10.1007/s11060-018-03084-w

Murdaugh, D., King, T.Z., & O’Toole, K. (2019). The efficacy of a pilot pediatric cognitive remediation summer program to prepare for transition of care. Child Neuropsychology, 25(2), 131-151. DOI:10.1080/09297049.2017.1391949

Semmel, E.S., Dotson, V., Burns, T.G., Mahle, W.T., King, T.Z. (2018). Cerebellar Volume and Executive Function in Congenital Heart Disease. Journal of the International Neuropsychological Society, Special Edition Neurodevelopmental Disorders, 24(9), 939-948. DOI 10.1017/S1355617718000310

Fox, M.E., & King, T.Z. (2018). Functional connectivity in adult brain tumor patients and survivors: A review. Brain Connectivity, 8(7), 381-397. DOI:10.1089/brain.2018.0623.

Ailion, A.S., Hortman, K., & King T.Z. (2017). Childhood brain tumors: A systematic review of the structural neuroimaging literature. Neuropsychology Review, 27(3), 220-244. DOI: 10.1007/s11065-017-9352-6

King T.Z., Na, S., & Mao, H. (2015). Neural underpinnings of working memory in adult survivors of childhood brain tumors. Journal of the International Neuropsychological Society, 21(7), 494-505.

King, T.Z., Wang, L., Mao, H. (2015). White Matter Integrity Disruption in Normal Appearing White Matter: Correlates with long-term intellectual outcomes of childhood brain tumor survivors. PLoS One, 10(7): e0131744.