Ph.D., University of Florida, 2000
My research program investigates the interacting biopsychosocial factors that contribute to optimal adaptive outcomes following neurodevelopmental disruption. My interest in brain-behavior relationships is broad, spanning a wide range of research methods, psychological domains, and populations. My research is focused on discovering what happens to the developing brain and to cognitive abilities across the lifespan many years after disorder onset (e.g., brain tumor, congenital heart disease). My team and I investigate white matter pathways using diffusion tensor imaging (DTI) and brain region activations using functional MRI (fMRI) to examine the neural mechanisms underlying both cognitive and social-emotional abilities of individuals. While I initially employed this comprehensive framework to examine the long-term outcomes of survivors of childhood brain tumors, I have extended components of this work to other neurodevelopmental disorders by investigating predictors of adaptive outcomes, neuroimaging studies of cognition, and psychophysiological and neuroimaging studies of emotion.
In 2013, my team and I successfully completed the 6-year Research Scholar Grant awarded by the American Cancer Society (ACS) for this program of research. One new extension of this research is a project in collaboration with Dr. Tobey McDonald, funded by AFLAC Center and Children’s Health Care of Atlanta (CHOA)’s Pediatric Hematology/Oncology Center of Excellence, that examines single nucleotide polymorphisms relationship with cognitive and neuroimaging outcomes of survivors of cerebellar brain tumors. In 2016, we expanded this research with Drs. Phan and Siegel to also examine how these factors relate to sleep outcomes in survivors (funded by CHOA’s Center for Neurosciences Research).
Many of my students have developed clinical neuropsychological evaluation skills and research projects while contributing to these projects. See the video of our research team http://www.gsu.edu/2013/08/12/grad-student-probes-the-mysteries-of-the-brain-and-behavior/ (at bottom of webpage); at the GSU / Ga Tech Center for Advanced Brain Imaging, where we conduct our research (http://www.cabiatl.com/CABI/).
In addition, I collaborate with a large group of scientists in the Center for Behavioral Neuroscience (http://www.cbn-atl.org/) on a project on How the Brain Expresses Positive Emotions funded from the Templeton Foundation that examines the role of oxytocin on empathy and social cognition using an innovative neuroimaging paradigm. http://news.gsu.edu/2013/08/21/scientists-receive-3-4-million-to-study-how-brain-expresses-positive-emotions/.
In August 2016, my GSU colleagues (Drs. Latzman and Chan) and I have joined a large multisite consortium study aimed at developing an outcome severity measure and biomarkers for the study of Rett Syndrome (funded by the Rett Syndrome Research Trust). http://reverserett.org/research/consortia/outcome-measures-and-biomarkers-development/ We are developing a much-needed sensitive outcome severity scale that will measure change over time in future clinical trial research with this population. This collaboration builds upon my interests in optimizing outcomes of individuals with neurodevelopmental conditions across the lifespan.
Recent Representative Peer Reviewed Publications
Student mentee co-authors’ names are italicized.
Taiwo, Z., Na, S., & King, TZ. (in press) The Neurological Predictor Scale: A predictive tool for neurocognitive late effects in survivors of childhood brain tumors. Pediatric Blood and Cancer.
Fox, M. & King, TZ. (in press; Early view pub 7.28.2016) Pituitary disorders as a predictor of apathy and executive dysfunction in adult survivors of childhood brain tumors. Pediatric Blood and Cancer. DOI: 10.1002/pbc.26144.
King, T.Z., Smith, K., Burns, T., Sun, B., Shin, J., Jones, R., Drossner, D., Mahle, W. (in press). FMRI investigation of working memory in emerging adults with surgically treated congenital heart disease. Applied Neuropsychology: Child. http://www.tandfonline.com/doi/abs/10.1080/21622965.2015.1065185
Fani, N., King, T.Z., Shin, J., Srivastava, A., Brewster, R.C., Stevens, J.S., Jovanovic, T., Bradley, B., Ressler, K.J. (2016). Structural and functional connectivity and Posttraumatic Stress Disorder: Associations with FKBP5. Depression and Anxiety, 33(4), 300-307.
King, T.Z., & Na., S. (2016). Cumulative Neurological Factors Predict Long-term Outcomes in Adult Survivors of Childhood Brain Tumors. Child Neuropsychology, 22(6),748-760. http://dx.doi.org/10.1080/09297049.2015.1049591
Chen, H., Wang,L., King, T.Z., & Mao, H. (2016). Increased frontal functional networks in adult survivors of childhood brain tumors. Neuroimage: Clinical,11, 339-346. http://dx.doi.org/10.1016/j.nicl.2016.02.010
Ailion, A.S., King, T.Z., Wang, L., Fox, M., Mao, H., Morris, R.M., Crosson, B. (2016). Cerebellar Atrophy in Adult Survivors of Childhood Cerebellar Tumor. Journal of the International Neuropsychological Society, 23, 1-11. doi:10.1017/S1355617716000138
King T.Z., Na, S., & Mao, H. (2015). Neural underpinnings of working memory in adult survivors of childhood brain tumors. Journal of the International Neuropsychological Society, 21(7), 494-505. http://dx.doi.org/10.1017/S135561771500051X
King, T.Z., Smith, K., & Ivanisevic, M. (2015). The mediating role of visuospatial planning skills on adaptive function among young-adult survivors of childhood brain tumor. Archives of Clinical Neuropsychology, 30(5), 394-403. http://dx.doi.org/DOI:10.1093/arclin/acv033
King, T.Z., Wang, L., Mao, H. (2015). White Matter Integrity Disruption in Normal Appearing White Matter: Correlates with long-term intellectual outcomes of childhood brain tumor survivors. PLoS One, 10(7): e0131744. journals.plos.org//plosone/article?id=10.1371/journal.pone.0131744
Brewster, R., King, T.Z., Burns, T., Drossner, D., & Mahle, W.T. (2015). White matter integrity dissociates auditory attention span and verbal memory in emerging adults with congenital heart disease. Journal of the International Neuropsychological Society, 21, 22-33.
Jayakar, R., King, T.Z., Morris, R., & Na, S. (2015). Hippocampal volume and auditory attention on a verbal memory task with adult survivors of pediatric brain tumor. Neuropsychology, 29(2), 303-319.
Fani, N., King, T.Z., Brewster, R., Srivastava, A., Stevens, J.S., Glover, E., Norrholm, S.D., Ressler, K.J., & Jovanic, T. (2015). Fear potentiated startle during extinction is associated with white matter microstructure and functional connectivity. Cortex, 64, 249-259.
Smith K.M., King T.Z., Jayakar, R., & Morris, R.D. (2014). Reading skill in adult survivors of childhood brain tumor: A theory-based neurocognitive model using DTI. Neuropsychology, 28(3), 448-458.
Fani, N., King, T.Z., Reiser, E., Binder, E., Jovanovic, T., Bradley, R., & Ressler, K. (2014). FKBP5 Genotype and Structural Integrity of the Posterior Cingulum. Neuropsychopharmacology, 39(5):1206-13.
Rozga, A., King, T.Z., Vuduc, R.W., & Robins, D.L. (2013). Undifferentiated Facial Electromyography Responses to Dynamic, Audio-Visual Emotion Displays in Individuals with Autism Spectrum Disorders. Developmental Science, 16(4), 499-514.
Micklewright, J.L., King, T.Z., O’Toole, K., Henrich, C., & Floyd, F.J. (2012). Parental distress, parenting practices, and child adaptive outcomes following traumatic brain injury. Journal of the International Neuropsychology Society, 18, 1-8.